Prospective, Multicenter, Comparative, Paired Study to Validate a microRNA-based Fecal Test for Colorectal Cancer Screening. The miRFec Study
The present study aims to compare effectiveness and cost-effectiveness of the miRFec test with respect to fecal immunochemical test (FIT) for the detection of advanced colorectal neoplasm among individuals participating in colorectal cancer (CRC) screening, surveillance and diagnosis.
• Male or female aged 50 to 75 (average-risk) referred to colonoscopy-based CRC screening.
• Male or female aged 30 to 80 with family history of CRC (moderate-risk) referred to colonoscopy-based CRC screening.
• Male and female aged 18 or older with personal history of colorectal polyps referred to colonoscopy surveillance.
• Male and female aged 18 or older with personal history of CRC referred to colonoscopy surveillance.
• Male and female aged 18 or older with colorectal symptoms referred to diagnostic colonoscopy.